

Drex DeFord
Principal
229Project
About Drex
I'm a farm-kid from Indiana. With no money for college, I enlisted in the Air Force as an IT Specialist. While on active-duty and working full-time, I finished my undergrad in Business (Magna Cum Laude), and my first masters degree (Public Administration). The Air Force offered a direct commission as a USAF Officer (hospital administration) -- and I accepted. As a USAF officer, I was the CIO at a small hospital; the Administrator of an Air Transportable Hospital (like an Air Force version of a MASH unit) during Desert Shield/Storm -- shot at and missed; Deputy CIO at the USAF School of Healthcare Sciences; completed a second masters (MS in Health Informatics), CIO at the Air Force's Largest Regional Command (14 hospitals and clinics across the Southern US); CIO at one of the AF's largest Medical Centers; went back to the Middle East to lead an expeditionary hospital supporting multi-national warfighters enforcing Iraqi No-Fly-Zone Operations (Operation Southern Watch); then off to Washington DC as the Chief Technology Officer for Air Force Health System's World-Wide Operations. After 20 years and 21 days of military service I retired from the USAF, and started a civilian career that's included CIO roles at Scripps Health, Seattle Children's, and Steward Healthcare, and CEO of Next Wave Connect. I hung out my shingle as an independent consultant, launching drexio digital health in early 2015. Now, I am joining the This Week Health team as the President of 229, Risk and Security.
Episodes featuring Drex
311 episodes


Innovating Beyond Frustration | UnHack the Podcast with Anahi Santiago and Krista Arndt

The Front Door Is Wide Open: Healthcare's IAM Wake-Up Call | Executive Interview with Mark Ferrari

Why Refusing to Change Is Riskier Than Embracing Agentic AI | Newsday

The Entry-Level Job Crisis, Consulting Collapse, and Shadow AI | Newsday

UnHack Rewind 2025: The Year Healthcare Cybersecurity Grew Up

What Healthcare Can Learn From a 20 Year Old Hacker | 2 Minute Drill with Drex DeFord

Healthcare IT Is Drowning in Projects, Here’s Why | Newsday

The Most Likely Way Into Your Network Is Still the Door You Forgot to Lock | 2 Minute Drill

2 Minute Drill: How a 22-Year-Old Took Down the World's Largest Botnet with Drex DeFord

2 Minute Drill: AI has now Hacked the Un-hackable with Drex DeFord
